National cultural capital as out of reach for transnationally mobile Israeli professional families - making a 'return home' fraught

The potentiality of converting capitals in new national fields following migration has been the focus of a number of studies. Another, much smaller, literature examines experiences of return migration. In this paper, we follow 15 Israeli families (where both mothers and children have been interviewed) who have been globally mobile for professional reasons. We examine cultural capital accumulation strategies for the children and how these facilitate the occupation of advantageous social positions while abroad. Having returned to Israel, partly due to the COVID pandemic, the national cultural capital the families have so actively cultivated in their children is evaluated as not authentic enough. Meanwhile, the cosmopolitan cultural capital that has been so valorised abroad, is not recognised as something the children can draw on to position themselves either. The paper contributes to the study of return migration, with a unique focus on globally mobile families returning 'home'. We also examine how national cultural capital is conceived and differentially assessed as families move from a more transnational space to that of their home country.

Is a Video Worth a Thousand Words? Educating Preclinical Medical Students on Sterile Scrubbing, Gowning, and Gloving Virtually and In-Person.

INTRODUCTION: Programs that offer early exposure to surgery for medical students foster interest in and positive perceptions of surgery. The COVID-19 pandemic led to suspension of these activities at our institution, the University of Kansas School of Medicine. In response to the lack of virtual alternatives, a pilot virtual surgery enrichment program was implemented for first-year students in place of in-person surgical exposure. The aim of this study was to compare the efficacy of in-person and virtual-based surgical education programs to expose preclinical medical students about the surgical realm of medicine. METHODS: First-year medical students participated in either a virtual (Group A) or in-person (Group B) week-long surgical enrichment program. Group assignments were dictated by COVID restrictions on each of our three medical school campuses: Salina, Wichita, and Kansas City. Pre- and post-surveys with a 14-question multiple-choice assessment of surgical knowledge were distributed to participants. Paired Wilcoxon Signed Rank tests and Mann-Whitney-U tests were used for statistical analysis. RESULTS: There were 14 participants in Group A and 7 participants in Group B. Both groups improved significantly from pre- to post-assessment score. (Group A, p = 0.01; Group B, p = 0.04). There was no difference between groups in the magnitude of score improvement from pre- to post-assessment (p = 0.59). CONCLUSIONS: This pilot program demonstrated that virtual platforms can be a method to provide meaningful clinical experiences in surgery to preclinical medical students restricted from clinical activities. Further development of mentorship in virtual surgical programs and assessment of subjective experience is needed.

Nurturing mobilities: Family travel in the 21st century

Nurturing Mobilities employs new empirical material and an innovative theoretical framing to bring new clarity to why families travel today – and what happens when they do. The authors argue that an imperative to ‘think with mobility’ and to ‘aspire to be mobile’ shapes identities, futures, and family practices. Drawing on data that examines family travel practices – typically short-term trips – across the working-, middle-, and globally mobile middle-classes, Nurturing Mobilities describes how families travel, why they travel, and the role young family members play in curating family travel. Vitally, it examines the two biggest contemporary issues in global mobility: COVID-19 and climate change. How has COVID-19 changed travel motivations in a world beset by lockdowns and diminished finances? How are concerns around climate change, and engagements with global citizenship education, changing family travel practices? Nurturing Mobilities illuminates new ways in which social class divergence is forged through movements across borders. The authors’ theoretically inter-disciplinary approach delivers a full analysis of the apparently divergent processes that differentiate family travel along social class lines, yet also allow travel to play a core role in social mobility. This book is a vital resource for scholars and students studying mobility, globalisation, social class, and climate change engagement. © 2022 Claire Maxwell, Miri Yemini and Katrine Mygind Bach.

Neutrophil extracellular traps enhance macrophage killing of bacterial pathogens.

Neutrophils and macrophages are critical to the innate immune response, but cooperative mechanisms used by these cells to combat extracellular pathogens are not well understood. This study reveals that S100A9-deficient neutrophils produce higher levels of mitochondrial superoxide in response to Staphylococcus aureus and, as a result, form neutrophil extracellular traps (suicidal NETosis). Increased suicidal NETosis does not improve neutrophil killing of S. aureus in isolation but augments macrophage killing. NET formation enhances antibacterial activity by increasing phagocytosis by macrophages and by transferring neutrophil-specific antimicrobial peptides to them. Similar results were observed in response to other phylogenetically distinct bacterial pathogens including Streptococcus pneumoniae and Pseudomonas aeruginosa, implicating this as an immune defense mechanism that broadly enhances antibacterial activity. These results demonstrate that achieving maximal bactericidal activity through NET formation requires macrophages and that accelerated and more robust suicidal NETosis makes neutrophils adept at increasing antibacterial activity, especially when A9 deficient.

Pregnancy and COVID-19: pharmacologic considerations.

In this review, we summarize evidence regarding the use of routine and investigational pharmacologic interventions for pregnant and lactating patients with coronavirus disease 2019 (COVID-19). Antenatal corticosteroids may be used routinely for fetal lung maturation between 24 and 34 weeks' gestation, but decisions in those with critical illness and those < 24 or > 34 weeks' gestation should be made on a case-by-case basis. Magnesium sulfate may be used for seizure prophylaxis and fetal neuroprotection, albeit cautiously in those with hypoxia and renal compromise. There are no contraindications to using low-dose aspirin to prevent placenta-mediated pregnancy complications when indicated. An algorithm for thromboprophylaxis in pregnant patients with COVID-19 is presented, which considers disease severity, timing of delivery in relation to disease onset, inpatient vs outpatient status, underlying comorbidities and contraindications to the use of anticoagulation. Nitrous oxide may be administered for labor analgesia while using appropriate personal protective equipment. Intravenous remifentanil patient-controlled analgesia should be used with caution in patients with respiratory depression. Liberal use of neuraxial labor analgesia may reduce the need for emergency general anesthesia which results in aerosolization. Short courses of non-steroidal anti-inflammatory drugs can be administered for postpartum analgesia, but opioids should be used with caution due to the risk of respiratory depression. For mechanically ventilated pregnant patients, neuromuscular blockade should be used for the shortest duration possible and reversal agents should be available on hand if delivery is imminent. To date, dexamethasone is the only proven and recommended experimental treatment for pregnant patients with COVID-19 who are mechanically ventilated or who require supplemental oxygen. Although hydroxycholoroquine, lopinavir/ritonavir and remdesivir may be used during pregnancy and lactation within the context of clinical trials, data from non-pregnant populations have not shown benefit. The role of monoclonal antibodies (tocilizumab), immunomodulators (tacrolimus), interferon, inhaled nitric oxide and convalescent plasma in pregnancy and lactation needs further evaluation. © 2020 The Authors. Ultrasound in Obstetrics & Gynecology published by John Wiley & Sons Ltd on behalf of International Society of Ultrasound in Obstetrics and Gynecology.